GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs1971762 | 1 | rs3892761 | chr12:54070445 | ATP5G2 | chr12:54058945-54070512:- | 0.22 | 4.78 | 2.54E-6 | Height |
| BLCA | cis | rs9457247 | 1 | rs389946 | chr6:167407268 | RNASET2 | chr6:167343008-167412795:- | -0.25 | -5.16 | 4.07E-7 | Crohn's disease |
| BLCA | cis | rs9457247 | 1 | rs389956 | chr6:167407254 | RNASET2 | chr6:167343008-167412795:- | -0.25 | -5.16 | 4.07E-7 | Crohn's disease |
| BLCA | cis | rs7714584 | 1 | rs3900064 | chr5:150264414 | LOC134466 | chr5:150310000-150326146:- | -0.42 | -5.48 | 7.88E-8 | Crohn's disease |
| BLCA | cis | rs7714584 | 1 | rs3906527 | chr5:150266392 | LOC134466 | chr5:150310000-150326146:- | 0.47 | 6.24 | 1.17E-9 | Crohn's disease |
| BLCA | cis | rs7714584 | 1 | rs3906528 | chr5:150266718 | LOC134466 | chr5:150310000-150326146:- | 0.47 | 6.24 | 1.17E-9 | Crohn's disease |
| BLCA | cis | rs7655841 | 1 | rs391396 | chr4:130037653 | C4orf33 | chr4:130014829-130033842:+ | -0.35 | -5.79 | 1.47E-8 | Chronic obstructive pulmonary disease (moderate to severe) |
| BLCA | cis | rs3931020 | 1 | rs3931020 | chr1:75235317 | CRYZ | chr1:75171175-75199092:- | -0.28 | -4.46 | 1.07E-5 | Resistin levels |
| BLCA | cis | rs10935120 | 1 | rs3932818 | chr3:134206069 | ANAPC13 | chr3:134196547-134204865:- | 0.47 | 7.39 | 9.45E-13 | Height |
| BLCA | cis | rs9815354 | 1 | rs3934103 | chr3:41977214 | ULK4 | chr3:41288091-42003660:- | -0.61 | -9.43 | 3.93E-19 | Diastolic blood pressure |
| BLCA | cis | rs9894429 | 1 | rs3935543 | chr17:79579874 | TSPAN10 | chr17:79609349-79615778:+ | 0.49 | 8.84 | 3.52E-17 | Eye color traits |
| BLCA | cis | rs9457247 | 1 | rs393558 | chr6:167397750 | RNASET2 | chr6:167343008-167412795:- | -0.24 | -5.1 | 5.43E-7 | Crohn's disease |
| BLCA | cis | rs9457247 | 1 | rs393727 | chr6:167398632 | RNASET2 | chr6:167343008-167412795:- | -0.24 | -5.1 | 5.41E-7 | Crohn's disease |
| BLCA | cis | rs9457247 | 1 | rs394522 | chr6:167398071 | RNASET2 | chr6:167343008-167412795:- | -0.24 | -5.1 | 5.43E-7 | Crohn's disease |
| BLCA | cis | rs2028299 | 1 | rs3960018 | chr15:90383307 | AP3S2 | chr15:90373832-90456222:- | -0.7 | -10.62 | 2.88E-23 | Type 2 diabetes |